naloxone

Rhode Island reports 219 overdose deaths in 2025, a 50% decline since 2022 and the lowest number in over a decade, surpassing the state's 2030 reduction goal.

Massachusetts achieves historic milestone as opioid-related overdose deaths drop to 978 in 2025 — a nearly 60% decline from the 2022 peak.

DEA identifies 5-chloro desmethyl chlorphine—a new class of ultra-potent synthetic opioids—in Tennessee seizure. Learn the risks and how to stay safe.

DEA issues urgent safety advisory as fentanyl is increasingly combined with xylazine, nitazenes, cychlorphine, and medetomidine—substances that can defeat standard overdose reversal.

CDC data shows overdose deaths dropped to under 70,000 in 2025 — the lowest since 2019. Alabama, New York, and Virginia see 25-30% declines, while Arizona and New Mexico experience alarming spikes.

SAMHSA's April 2026 guidance prohibits federal grant funds from purchasing fentanyl test strips. Learn what this means for harm reduction programs and how to stay safe.

Twelve suspected overdose deaths in five days prompt urgent public health warning in Cincinnati area. What families need to know about the risks and how to respond.

CDC and DEA warn that medetomidine — a potent veterinary sedative — is spreading in the illegal fentanyl supply, causing severe withdrawal and complicating overdose response.

Federal health officials warn about cychlorphine, a potent synthetic opioid linked to 55+ deaths nationwide. Learn the risks, recognition signs, and life-saving response strategies.